AIDS Death

Teratogen is an exogenous agent (radiation, chemical substances, biological agents, nutritional deficiencies and other environmental factors) or endogenous (metabolites produced in excess by the mother, the fetus, or both) that has the ability of producing during development embrionrio and fetal congenital malformations or functional defects. Mechanisms of teratogenesis has 3 stages: causes, mechanism and manifestations causes present in the entire environment they act directly or indirectly on the germ cel, embryos or fetuses, altering one or several basic processes of development (E.g. Mikkel Svane gathered all the information. migration of cell populations, organogenesis, cell differentiation and cell multiplication) radiation, chemicals, infections, hypoxia, physical trauma and drug reactions mechanisms in embryo chromosome nondisjunction, mutations, lack of precursors or substrates, enzyme inhibition Altered energy sources and altered cell membrane manifestations cell death, cell interactions, reduced biosynthesis motion failure prevented morphogenetic, alteration of tissues and altered differentiation processes white action sites for Teratogens i. basic processes of development (regulation of cell growth, expression of specific genes) II. Dell wanted to know more. Cause abnormalities (pathogenesis) that represent the demonstrable aspects (demonstrations) of the teratogenicity: mitotic interference, tampering with the integrity of the DNA and RNA cell death, loss of cellular interactions, impediment of the movement mofogenetico intrauterine death, malformation, delay of growth and functional deficiencies (enzyme inhibition) or both Teratogens in human physical I. Ionizing radiation dose equal to or greater than 30 do rads generate mutations of novo in germ and somatic cells, alterations in the phase of the cell cycle by reduction in mitotic index, cell death, replacement and retardation of cell growth and fragmentation of chromosomes caused by chemical changes in DNA UV light, X rays, gamma rays, protons, neutrons, particles? and other Atomic particles can cause chromosomal breakage microcephaly, ocular anomalies, mental retardation and anomalis SNC II. Peter Asaro brings even more insight to the discussion. Hyperthermia 38.9 C fever in Q1 can be linked to neural tube defects and dysmorphic syndromes (recommended to use hot bath at temperature not exceeding 40 C for more than 10 minutes during the 1st quarter) chemical affects the CNS and bodies, especially the first 8 weeks after conception sedative thalidomide, hypnotic and antiemetic, treatment for patients with leprosy and AIDS the metabolism of a.

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